Four Cheese Pepperoni Pizza Knots Recipe

Cheesy Bliss: Four Cheese Pepperoni Pizza Knots Recipe

Crafting delectable four cheese pepperoni pizza knots becomes an irresistible culinary adventure that sparks joy in every kitchen.

Soft dough twists packed with melty cheese promise an explosion of flavor in each bite.

Childhood memories of pizza nights blend perfectly with this innovative appetizer approach.

Pepperoni adds a zesty punch that makes these knots impossible to resist.

Little hands and big appetites will converge around this simple yet spectacular dish.

Cheese lovers unite – you are about to experience a mouthwatering creation that elevates casual snacking into a gourmet moment.

This recipe guarantees smiles and empty plates in record time.

What Makes Four Cheese Pepperoni Pizza Knots Irresistible

  • Craft with Ease: No complicated techniques required, perfect for home cooks at any skill level.
  • Crowd-Pleasing Delight: Pepperoni and four-cheese combination creates an irresistible appetizer that appeals to all ages and tastes.
  • Quick Preparation Power: From mixing ingredients to pulling out of the oven, this recipe delivers maximum flavor with minimal effort.
  • Versatile Party Superstar: Ideal for game days, family gatherings, potlucks, or casual weekend snacking with friends.

Everything You Need For Four Cheese Pepperoni Pizza Knots

For the Dough:
  • Bread Flour: Provides strong gluten structure for a chewy and robust texture.
  • All-Purpose Flour: Helps create a balanced and soft dough consistency.
  • Active Dry Yeast: Essential for dough rising and developing complex bread flavors.
  • Warm Water: Activates and feeds the yeast for proper fermentation.
For the Seasoning:
  • Salt: Enhances overall flavor profile of the pizza knots.
  • Dried Oregano: Adds classic Italian herb note to the dough.
  • Garlic Powder: Provides a subtle, aromatic background flavor.
For the Filling and Topping:
  • Pepperoni, Mozzarella Cheese, Parmesan Cheese, Provolone Cheese, Cheddar Cheese: Creates a rich, melty, and flavorful filling.
For the Additional Ingredients:
  • Olive Oil: Adds moisture and helps develop soft dough texture.
  • Melted Butter, Fresh Parsley: Provides final garnish and aromatic finish.

How To Make Four Cheese Pepperoni Pizza Knots

Step 1: Awaken The Yeast

Create a warm bath for yeast in water heated to 110°F. Watch the mixture transform into a foamy, bubbly state within 5-7 minutes, signaling the yeast is ready to work its magic.

Step 2: Mix Dry Ingredients

Combine your flour blend:
  • Bread flour
  • All-purpose flour
  • Salt
  • Dried oregano
  • Garlic powder

Create a welcoming crater in the center of these dry ingredients.

Step 3: Blend Wet and Dry Ingredients

Pour the activated yeast and olive oil into the flour crater. Stir and fold until a soft, slightly sticky dough emerges.

Step 4: Knead The Dough

Transfer the dough to a floured surface. Knead vigorously for 8-10 minutes, developing a smooth and elastic texture that springs back when touched.

Step 5: First Rise

Place the dough in a lightly oiled bowl. Cover with a damp cloth and let it rest in a warm spot for 60-75 minutes until it doubles in size.

Step 6: Shape The Dough

Deflate the risen dough and roll it into a rectangular shape, aiming for about 1/4 inch thickness.

Step 7: Load With Toppings

Scatter across the dough:
  • Chopped pepperoni
  • Four cheese varieties

Leave a small border around the edges.

Step 8: Roll And Slice

Tightly roll the dough into a log. Slice into 1-inch thick rounds using a sharp knife.

Step 9: Prepare For Baking

Arrange knots on a parchment-lined baking sheet, giving them space to expand.

Step 10: Second Rise

Let the knots rest at room temperature for 20 minutes.

Step 11: Bake To Perfection

Preheat oven to 425°F. Bake knots for 15-18 minutes until golden brown with melted, bubbly cheese.

Step 12: Final Touch

Brush hot knots with melted butter and sprinkle fresh parsley on top.

Step 13: Serve And Enjoy

Allow knots to cool for 5 minutes before serving, letting flavors harmonize.

Top Tips For Four Cheese Pepperoni Pizza Knots

  • Activate Yeast Perfectly: Ensure water temperature is exactly 110°F to wake up yeast without killing it, creating a frothy base for soft, fluffy pizza knots.
  • Develop Dough Strength: Knead the dough thoroughly for 8-10 minutes to build gluten structure, resulting in a stretchy, tender texture that holds cheese and toppings beautifully.
  • Control Moisture Balance: Add flour gradually while kneading to prevent sticky dough, aiming for a smooth, elastic consistency that's easy to handle and shape.
  • Layer Cheese Strategically: Distribute cheese evenly across the dough to guarantee melted pockets in every bite, preventing dry or overly cheesy sections.

Delicious Variations Of Four Cheese Pepperoni Pizza Knots

  • Gluten-Free Herb Knots: Replace bread and all-purpose flour with a gluten-free flour blend, adding xanthan gum for better texture and structure.
  • Vegan Cheese Knots: Substitute dairy cheeses with plant-based mozzarella, nutritional yeast, and dairy-free pepperoni alternatives for a completely vegan version.
  • Mediterranean Inspired Knots: Replace pepperoni with sun-dried tomatoes, crumbled feta cheese, and add chopped kalamata olives for a Greek-style flavor profile.
  • Low-Carb Cauliflower Knots: Use cauliflower pizza crust as a base, incorporating almond flour and reduced cheese quantities for a lower-carbohydrate option.

What To Pair With Four Cheese Pepperoni Pizza Knots

  • Pair Spicy Marinara Dip: Create a zesty tomato-based sauce with red pepper flakes, garlic, and fresh basil to complement the cheesy, pepperoni-packed pizza knots.
  • Recommend Crisp Pilsner Beer: Select a light, refreshing beer with subtle hoppy notes that cuts through the rich cheese and spicy pepperoni flavors, cleansing the palate.
  • Serve Tangy Herb Salad: Craft a light side salad with mixed greens, lemon vinaigrette, and fresh herbs like parsley and oregano to balance the knots' heaviness.
  • Choose Chilled Pinot Grigio: Pour a crisp white wine with bright acidity that enhances the knots' cheesy texture and provides a refreshing counterpoint to the dish's richness.

How To Keep Four Cheese Pepperoni Pizza Knots Fresh

  • Store leftover pizza knots in an airtight container for up to 3-4 days. Wrap each layer with parchment paper to prevent sticking and maintain freshness.
  • Place cooled pizza knots in a freezer-safe container or zip-lock bag. Label with the date and consume within 2 months for best quality. Separate layers with wax paper to prevent freezer burn.
  • Preheat oven to 350°F. Arrange pizza knots on a baking sheet, cover loosely with foil to prevent drying. Warm for 8-10 minutes until heated through and cheese melts.
  • Place pizza knots on a microwave-safe plate. Heat in 15-second intervals, checking to avoid overcooking.

Four Cheese Pepperoni Pizza Knots Questions Answered

  • Can I use instant yeast instead of active dry yeast?

Yes, you can substitute instant yeast. Use the same amount, but skip the activation step since instant yeast doesn’t require proofing.

  • How do I know the dough is properly kneaded?

The dough should feel smooth, elastic, and spring back when gently pressed. It should no longer stick to your hands after 8-10 minutes of kneading.

  • What if my dough doesn't rise correctly?

Ensure your yeast is fresh and the environment is warm (around 75-80°F). A draft-free, slightly humid area works best for optimal dough rising.

  • Can I prepare the pizza knots ahead of time?

Yes, you can assemble the knots and refrigerate them overnight. Let them come to room temperature and rise before baking for best results.

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Four Cheese Pepperoni Pizza Knots Recipe

Four Cheese Pepperoni Pizza Knots Recipe


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4.8 from 23 reviews

  • Total Time: 80-113 minutes
  • Yield: 6 1x

Description

Gooey Four Cheese Pepperoni Pizza Knots blend Italian comfort with cheesy indulgence, creating a mouthwatering appetizer that promises pure culinary delight. Rolled with love and packed with savory flavors, you’ll savor each irresistible bite of this crowd-pleasing treat.


Ingredients

Scale

Main Ingredients:

  • 2 cups bread flour
  • 1/2 cup all-purpose flour
  • 1 packet active dry yeast
  • 1/2 cup pepperoni, chopped
  • 1/2 cup mozzarella cheese, shredded
  • 1/4 cup parmesan cheese, grated
  • 1/4 cup provolone cheese, shredded
  • 1/4 cup romano cheese, shredded

Liquid Ingredients:

  • 3/4 cup warm water
  • 2 tbsp olive oil

Seasoning and Garnish:

  • 1 tsp salt
  • 1 tsp dried oregano
  • 1 tsp garlic powder
  • 2 tbsp fresh parsley, chopped
  • 1 tbsp butter, melted

Instructions

  1. Activate the yeast by dissolving it in warm water (110°F), allowing it to foam and become frothy for approximately 5-7 minutes.
  2. In a large mixing bowl, combine bread flour, all-purpose flour, salt, dried oregano, and garlic powder, creating a well in the center for liquid ingredients.
  3. Pour the activated yeast mixture and olive oil into the flour mixture, blending until a soft, slightly sticky dough forms.
  4. Knead the dough on a floured surface for 8-10 minutes until smooth and elastic, developing gluten structure and achieving a springy texture.
  5. Transfer the dough to a lightly oiled bowl, cover with a damp cloth, and let rise in a warm environment for 60-75 minutes until doubled in size.
  6. Punch down the risen dough and roll it into a rectangular shape approximately 1/4 inch thick.
  7. Evenly distribute chopped pepperoni and all four cheese varieties across the dough’s surface, leaving a small border around the edges.
  8. Roll the dough tightly into a log, then slice into 1-inch thick rounds using a sharp knife.
  9. Arrange the pizza knots on a parchment-lined baking sheet, ensuring they are slightly separated to allow expansion.
  10. Let the knots rest and proof for an additional 20 minutes at room temperature.
  11. Preheat the oven to 425°F and bake the knots for 15-18 minutes until golden brown and cheese is melted and bubbly.
  12. Brush the hot knots with melted butter and sprinkle fresh parsley over the top for a vibrant finish.
  13. Allow the pizza knots to cool for 5 minutes before serving to let the cheese set and flavors meld.

Notes

  • Activate yeast precisely at 110°F to ensure proper fermentation and soft dough texture.
  • Choose high-protein bread flour for enhanced gluten development, creating a chewier, more structured pizza knot.
  • Experiment with alternative cheese combinations like mozzarella, provolone, parmesan, and fontina for diverse flavor profiles.
  • For gluten-free adaptation, substitute wheat flour with a blend of almond and gluten-free all-purpose flour, adding xanthan gum for binding.
  • Prep Time: 15-20 minutes
  • Cook Time: 15-18 minutes
  • Category: Lunch, Dinner, Appetizer, Snacks
  • Method: Baking
  • Cuisine: Italian

Nutrition

  • Serving Size: 6
  • Calories: 320
  • Sugar: 1 g
  • Sodium: 600 mg
  • Fat: 15 g
  • Saturated Fat: 6 g
  • Unsaturated Fat: 8 g
  • Trans Fat: 0 g
  • Carbohydrates: 36 g
  • Fiber: 1 g
  • Protein: 12 g
  • Cholesterol: 20 mg
Olivia Brooks

Olivia Brooks

Contributing Writer

Expertise

  • Healthy recipe development
  • Plant-based cooking
  • Nutritional analysis
  • Food writing and content creation

Education

Culinary Institute of America
Accelerated Culinary Arts Certificate Program
Focus: Culinary fundamentals, nutrition, and healthy cooking technique


Olivia believes good food should feed both the body and the soul. She earned her Accelerated Culinary Arts Certificate from the Culinary Institute of America, where she focused on nutrition and practical cooking techniques that make healthy eating easy.
At 10 Below Ice Cream, Olivia shares single-serving recipes that are fresh, plant-forward, and full of heart. She loves helping people eat better, without stress, strict rules, or sacrificing flavor.
Beyond the kitchen, Olivia spends her time tending her backyard garden, practicing yoga, and discovering hidden gems in Portland’s food scene.

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