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Pepperoni Pizza Casserole Recipe

Pepperoni Pizza Casserole Recipe


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4.8 from 9 reviews

  • Total Time: 40 minutes
  • Yield: 4 1x

Description

Hearty pepperoni pizza casserole brings classic Italian-American comfort to dinner tables with layered pasta, zesty sauce, and melted cheese. Cheese-loving families will devour this one-pan wonder that combines pizza flavors in a satisfying, easy-to-serve casserole you can’t resist.


Ingredients

Scale

Pizza Base:

  • 2 cups pasta (penne or rotini)
  • 1 cup marinara sauce
  • 2 cups shredded mozzarella cheese

Meat and Toppings:

  • 6 oz pepperoni slices
  • 1/2 cup diced green bell peppers
  • 1/4 cup sliced black olives

Seasoning and Extras:

  • 1 tsp dried oregano
  • 1/2 tsp garlic powder
  • 1/4 tsp red pepper flakes
  • 2 tbsp olive oil
  • Salt to taste
  • Black pepper to taste

Instructions

  1. Preheat the oven to 375°F and lightly grease a 9×13-inch baking dish to ensure easy serving and prevent sticking.
  2. Cook the pasta in salted boiling water until al dente, typically 8-10 minutes, then drain thoroughly and return to the pot.
  3. Toss the cooked pasta with marinara sauce, creating a rich and evenly coated base for the casserole.
  4. Layer half of the sauced pasta into the prepared baking dish, creating a solid foundation for the pizza-inspired layers.
  5. Sprinkle a generous amount of mozzarella cheese over the pasta, ensuring complete coverage.
  6. Distribute pepperoni slices across the cheese layer, creating a classic pizza-like appearance and flavor profile.
  7. Scatter diced green bell peppers and sliced black olives evenly over the pepperoni, adding vibrant color and texture.
  8. Dust the layer with dried oregano, garlic powder, red pepper flakes, salt, and black pepper to enhance the overall seasoning.
  9. Add the remaining pasta on top, followed by another layer of mozzarella cheese and the remaining pepperoni.
  10. Drizzle olive oil over the top layer to promote golden browning and add a subtle richness.
  11. Bake in the preheated oven for 20-25 minutes, or until the cheese is completely melted and slightly bubbling with a golden-brown surface.
  12. Remove from the oven and let the casserole rest for 5 minutes before serving to allow the layers to set and flavors to meld.

Notes

  • Customize pepperoni portions for diet preferences, using turkey pepperoni or reducing quantity for lower-fat options.
  • Experiment with alternative cheese blends like part-skim mozzarella or adding sharp cheddar for deeper flavor complexity.
  • Create vegetarian version by replacing pepperoni with plant-based protein like roasted mushrooms or vegetarian sausage crumbles.
  • Prep casserole ahead and refrigerate unbaked, allowing flavors to intensify before final baking for enhanced taste development.
  • Prep Time: 15 minutes
  • Cook Time: 25 minutes
  • Category: Lunch, Dinner, Snacks
  • Method: Baking
  • Cuisine: Italian-American

Nutrition

  • Serving Size: 4
  • Calories: 600
  • Sugar: 4 g
  • Sodium: 1200 mg
  • Fat: 36 g
  • Saturated Fat: 14 g
  • Unsaturated Fat: 20 g
  • Trans Fat: 0 g
  • Carbohydrates: 50 g
  • Fiber: 3 g
  • Protein: 25 g
  • Cholesterol: 60 mg